Portuguese Version

Year:  1997  Vol. 63   Ed. 5 - ()

Artigos Originais

Pages: 469 to 475

Sinus Disease in Cystic Fibrosis.

Author(s): Otávio B. Piltcher*
Ângela E. Zucatto**
Daniela D. Rosa **
Lisângela C. Preissler**
Eduardo L. Hentschel**
Leonardo Q. da Paixão**

Keywords: cystic fibrosis, sinus disease, sinusitis, mucoviscidosis

Abstract:
Cystic fibrosis is one of the most common lethal inherited diseases that affects caucasians. Its mortality has been dramatically reduced over the last ten years as the result of an increased use of prophylaxis for recurrent upper respiratory infections and better control of patients by specialists. Sinus disease is radiologically detected in almost all patients, but only 50% are symptomatic. Ten to 20% of these patients undergo sinus surgery. All treatments are only temporarily effective. Surgeons must be conscious that surgical procedures are indicated for specific cases but the operations only change the sinus anatomy, while the main problem of the disease, the cellular disfunction, remains. The pathophysiology, clinical manifestations, diagnosis, prognosis, complications and management of sinus disease among patients with cystic fibrosis are discussed, pointing out the dispute aspects.

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