Year: 1999 Vol. 65 Ed. 5 - (5º)
Artigos Originais
Pages: 404 to 411
Auditory Brainstem Reponse in Asymptomatic HIV Positive Patients: Analysis of 11 and 61 Clicks per Second.
Author(s):
Marco A. M. T, Lima*;
Yotaka Fukuda**.
Keywords: auditory evoked potentials; ABR; HIV; AIDS
Abstract:
Introduction: The Auditory Brainstem Response (ABR) are evoked potentials that occur within a time frame of up 10 milliseconds in response to an auditory stimulus (clicks). Increasing the rate of stimulation prolongs the latencies of the waves by affecting the synaptic transmission, even in normal subjects. Purpose: This work had the objective to detect early abnormalities in the central nervous system of HIV asymptomatic patients (group II CDC -1986) by ABR at low (11 clicks/s) and high (61 clicks/s) stimulus rates. Material and Methods: Thirty (15 men and 15 women) asymptomatic HIV positive persons and thirty (15 men and 15 women) non HIV positive were studied. All patients underwent a thorough otolaryn-gological and clinical investigation to exclude any licit or ilicit drug use, past otological or neurological disease, diabetes mellitus, syphillis and renal insufficiency. ABR was applied at 100 dB peSPL intensity, with two consecutive stimulation rates of 11 and 61 clicks/s for each ear. The absolute peak latencies of the waves I, III and V and the interpeak latencies I-III, III-V and I-V were compared between the two groups and statistically evaluated by the Student's t test. The results showed that there were no significant differences in the ABR between the two groups neither in the low stimulus rate nor with a high stimulus rate. Conclusion: We concluded that ABR in the stimulus rate of 11 and 61 clicks per second is not an efficient method to detect early neurological abnormalities in asymptomatic HIV positive persons.
-
Print: 
