Keywords: Kallmann's syndrome, hypogonadism hypogonadotrophic, anosmia

Abstract: Kallmann's syndrome is characterized by hypogonadotrophic hypogonadism and anosmia or hyposmia. Its primary defect is an anomalous migration of the neurons responsible for the GnRH production and the neurons that compose the olfactory nerves. The syndrome affects the gonadotrophin production only, all other hypophysial hormones are normally secreted. In this paper we report and discuss two cases of Kallmann's syndrome in young women.