Keywords: epistaxis, oral hemorrhage, hereditary hemorrhagic telangiectasia, skin diseases, arteriovenous malformations, nose diseases

Abstract: Osler-Rendu-Weber syndrome, asso known as hereditary hemorrhagic telangectasia (HHT), is a dominant autossomic genetic disease, that leads to a vascular malformation. We report a case of this disease which leads patients to bleedings, mostly often epistaxis, in a 78 year old female patient. She presents, since childhood, many episodes of epistaxis, hemoptysis and chronic anemia. It has not been possible to make an angiography in order to investigaté vascular malformations in other organs, such as lungs, gastrointestinal tract, liver and brain. She has a transient ischemic attack (TIA), that could be related to the syndrome, with a normal brain computerized tomography. She has cardiac insufficiency level III. Between the therapeutic choices, we decided to use CO2 laserto treat the bleeding lesiorí.; in the tongue and nasal cavity. We achieved good results, with regression of the lesions and no new bleeding episodes.